100.Lung, polarizable crystals with intravenous drug use, polarized light microscopic
Bright white collections of polarizable crystals are seen here, but are diffuse and centered around vascular spaces. This is the lung of a patient with a long history of intravenous drug use. Only about 1% of such persons get a significant degree of pulmonary fibrosis. The crystals represent talc that is used to to dilute the injected drug.