双语教学

Explain of Immunopathology

1. Antinuclear antibody test, homogenous pattern, fluorescence microscopy

Screening for autoimmune diseases is often performed with the antinuclear antibody (ANA) test in which patient serum is incubated with a tissue substrate to which any autoantibodies to nuclear antigens will bind. Then, a fluorosceinated antibody is added and the tissue is observed under fluorescence microscopy to see if staining is present. Seen here is the typical "homogenous" pattern of nuclear staining of a positive ANA.

（本图片资料来源自美国犹他大学）