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Explain of Neoplasia
4. Columnar metaplasia, esophagus, microscopic
  This biopsy of the lower esophagus in a patient with chronic gastroesophageal reflux disease shows columnar metaplasia (Barrett's esophagus), and the goblet cells are typical of an intestinal type of epithelium. Squamous epithelium typical of the normal esophagus appears at the right.
(本图片资料来源自美国犹他大学)
   
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