83.Midbrain, normal and abnormal with Parkinson's disease compared, gross
The loss of pigmentation in the substantia nigra of the midbrain at the left in a patient with Parkinson's disease is contrasted with a normal midbrain at the right. Parkinson's disease is marked clinically by a "pill-rolling" tremor at rest, mask-like facies, and cogwheel rigidity of limbs, among other findings.